Non-alcoholic fatty liver disease (NAFLD) is a multifactorial chronic inflammatory disease involving multiple liver cell types that affects nearly one third of people worldwide. NAFLD can progress to more severe forms of liver disease such as non-alcoholic steatohepatitis (NASH) and fibrosis. However, there are currently no approved biomarkers or therapies. We are looking for a highly-motivated individual to drive cutting-edge research in modelling inflammation-driven health-to-disease in the NAFLD-to-NASH transition phase. You will be involved in human liver disease modelling including development of a unique, dynamic human liver acinus-on-a-chip system to unravel relevant molecular pathways, targets and biomarkers. Expertise and interest in tissue engineering (2D-3D organotypic models) and applying novel analytical approaches is highly desirable.
The appointee will be responsible for Facility operation and test design, including planning and carrying out experimental work and supporting students and clients at FastBlade. Managing workflow, maintenance, training, and safety within the FastBlade Facility. Liaising with other lab users and other university departments such as technical or financial services. Contribute to research work at FastBlade including analysis of results, publishing papers and presenting research and meetings and conferences.