Non-alcoholic fatty liver disease (NAFLD) is a multifactorial chronic inflammatory disease involving multiple liver cell types that affects nearly one third of people worldwide. NAFLD can progress to more severe forms of liver disease such as non-alcoholic steatohepatitis (NASH) and fibrosis. However, there are currently no approved biomarkers or therapies. We are looking for a highly-motivated individual to drive cutting-edge research in modelling inflammation-driven health-to-disease in the NAFLD-to-NASH transition phase. You will be involved in human liver disease modelling including development of a unique, dynamic human liver acinus-on-a-chip system to unravel relevant molecular pathways, targets and biomarkers. Expertise and interest in tissue engineering (2D-3D organotypic models) and applying novel analytical approaches is highly desirable.

UoE Vacancy Ref: 


Closing Date: 

Wednesday, October 4, 2023

Sprays in engineering applications: modelling and experimental studies

The sixth meeting of the UK Fluids Network SIG on Sprays was recently held at the University of Edinburgh's Pollock Halls on 16th August 2019.

image of downward spray emitted from nozzle of can at top left, with black background

Fresh insight into how the brain responds to medically induced cooling could inform treatments for head injuries and conditions such as stroke.

The study, carried out in 3D simulations, could also help babies at risk of birthing complications.

Head slice and vessel expansion probability maps

The exploration and development of deeper wells with heavier and more viscous oils, requiring greater operating pressures and more fracture to fissures to release the oils. This results in significantly increased sand content that has the potential to bring about a fundamental shift in flow behaviour. This project aims to investigate the potential – and develop – a coupled smooth particle hydrodynamics (SPH) and discrete element method (DEM) model to simulate high-pressure multi-phase flows with support from an extensive experimental programme and industrial collaboration.

Research Themes: 

  • Granular Mechanics and Industrial Infrastructure
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